Comparison

UpToDate vs Orphanet Guides

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

UpToDate

This clinical decision support tool provides healthcare professionals with evidence-based guidance to improve patient care. It features AI-powered conversational answers, continuously updated medical content, and tools for drug reference, calculations, and patient education.

Highlights
  • Expert AI conversational guidance
  • Gold standard clinical content
  • Practice-changing updates
  • Patient education materials
  • Drug reference and interactions
  • Clinical calculators
  • Kidney dosing guidance
Features
Read full description

UpToDate is the clinical decision support solution trusted by over 3M healthcare professionals to help improve care delivery and patient outcomes. Now powered by UpToDate Expert AI, a generative AI experience built on rigorously maintained UpToDate clinical intelligence to delivers fast, clinically grounded answers through a conversational interface. Expert AI, available in select packages and applications, brings together the latest evidence and real-world clinical expertise and provides transparent sourcing, embedded guardrails, and oversight, supporting clinical reasoning and helping clinicians make confident, informed decisions. Key features include: • Expert AI: Conversational guidance that mirrors how clinicians think. • Gold Standard Clinical Content: Clinician-authored clinical intelligence and graded recommendation, enriched with clinical algorithms, graphics, videos, and continuously updated to reflect the latest evidence and clinical care experience. • Practice-Changing Updates: Timely insights that reflect the latest evidence and how it impacts patient care. • Patient Education: Thousands of patient education leaflets in up to 19 different languages to improve patient understanding and support care plan adherence. • Key Points Panels: Quick, clinically actionable guidance to help clinicians avoid common diagnostic and treatment errors embedded in UpToDate search results. • Drug Reference & Interactions: Evidence-based drug monographs and interaction analysis to support safe and informed prescribing decisions. • Clinical Calculators: Over 200 tools to support dosing, risk scoring, and patient assessments. • Rx Transitions: Step-by-step support for switching antidepressants safely. • Kidney Dosing: Drug dosing guidance for patients with renal impairment. Available on mobile, desktop, and integrated into EHRs, ensuring you can access UpToDate’s trusted guidance where and when you need it. Access to features will vary depending on your UpToDate account. Expert AI is now available in personal trainee subscriptions and UpToDate Pro Plus subscriptions in the US, and through select Enterprise Edition accounts. To get access, explore personal subscription options on the UpToDate website or contact your Enterprise account lead. This app is designed for use by medical professionals. If you are not a medical professional, please consult a qualified healthcare provider before making any medical decisions.

About

Orphanet Guides

Access validated, practical information for medical professionals and others involved in rare disease care in France. This app provides articles on emergency care, disability support, and available aid and benefits for patients and their families.

Highlights
  • Validated medical information
  • Focus on rare diseases
  • Emergency care guidance
  • Disability support information
  • Aid and benefits synthesis
  • Offline access
  • Shareable articles
Features
Read full description

Orphanet Guides vous permet d'accéder gratuitement à une information validée, spécifique et pratique pour les professionnels médicaux, paramédicaux et toute personne concernée par la prise en charge d'une maladie rare en France. L'application est constituée de 3 catégories d'articles dédiés à la prise en charge des personnes atteintes de maladies rares: en situation d'urgence, en situation de handicap, synthèse des aides et prestations dont les personnes et leurs proches peuvent bénéficier. Orphanet Guides est développé par l'unité Inserm US-14 avec le soutien de la fondation Groupama et le concours du Plan National Maladies Rares et de la Caisse nationale de solidarité pour l'autonomie (CNSA). Les fiches d'information sont faciles à consulter, peuvent être partagées et téléchargées pour être utilisées y compris hors réseau.

Screenshots

UpToDate4 screens
Orphanet Guides4 screens

Verdict

The call

The clearest difference is rating: UpToDate at 3.6 against Orphanet Guides's 1.0. UpToDate also leads on review sentiment (28% vs 0%) and ratings volume (583 vs 1). Orphanet Guides's advantage is monetization model (free vs subscription) and iOS requirement (11.0 vs 18.0). On price, ads, in-app purchases and device support there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

ReceptionRating · Positive reviews · Number of ratings

UpToDate holds the better App Store score, 3.6 against 1.0. That said, the two scores are not equally well evidenced: UpToDate has 583 ratings behind it against 1, so its average is the more settled of the two. Written reviews point the same way: 28% of UpToDate's written reviews are positive against 0% of Orphanet Guides's.

Scorecard5 real differences · 5 level
UpToDate versus Orphanet Guides: the parameters behind the verdict, then further details
ParameterUpToDateOrphanet Guides
PriceFreeFree
Rating3.6 (583 ratings) — better1.0 (1 ratings)
Positive reviews28.4% of reviews — better0.0% of reviews
Number of ratings583 — better1
Update frequencyEvery 5 weeks—
AdsNoNo
In-app purchasesNoNo
MonetizationSubscriptionFree — better
DevicesiPhone, iPadiPhone, iPod
Requires iOS18.011.0 — better
Further details — not scored
Size56 MB61 MB
Age rating17+17+
DeveloperUpToDate, Inc.Inserm

Customer experience

UpToDate

All ratings579 ratings
Positive60.4%
Neutral10.4%
Negative29.2%
Written reviews384 reviews
Positive28.4%
Neutral9.6%
Negative62.0%

Orphanet Guides

All ratings1 ratings
Positive0.0%
Neutral0.0%
Negative100.0%
Written reviews1 reviews
Positive0.0%
Neutral0.0%
Negative100.0%

Bugs and requests

UpToDate

Reported bugs

3 issues
  • Inability to download offline content
  • Constant need to re-authenticate
  • Incompatibility with recent iOS updates

Requested features

3 requests
  • Highlight and annotate content
  • Improved institutional login support
  • Dark mode and font size options

Orphanet Guides

Not enough reviews yet to summarise bugs or requests.

In-app purchases

None

UpToDate

No in-app purchases

None

Orphanet Guides

No in-app purchases

Questions

Is UpToDate free?
UpToDate is free to download, with no in-app purchases.
Is Orphanet Guides free?
Orphanet Guides is free to download, with no in-app purchases.
Which has better reviews, UpToDate or Orphanet Guides?
UpToDate is rated higher. UpToDate averages 3.6 out of 5 from 583 ratings, while Orphanet Guides averages 1.0 from 1 ratings.
Do UpToDate or Orphanet Guides have ads?
Neither UpToDate nor Orphanet Guides shows ads.

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