Comparison

Sepsis Clinical Guide vs Safe Vent

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

Sepsis Clinical Guide

This app provides busy health professionals with essential management information for sepsis, based on the latest practice guidelines. It offers quick access to definitions, diagnostic criteria, and treatment protocols at the point of care. It also includes a community forum for clinicians to exchange ideas and collaborate on clinical topics.

Highlights
  • Latest sepsis definitions and diagnostic criteria
  • Management guidelines from Surviving Sepsis Campaign
  • Information on epidemiology and pathophysiology
  • Guidance on antibiotic therapy
  • Pediatric and neonatal sepsis management
  • Clinical community forum for collaboration
Features
Read full description

Sepsis Clinical Guide now includes access the new ESCAVO Clinical Community, a forum where clinicians can exchange ideas, ask questions and collaborate on sepsis and other clinical topics. Sepsis is a serious systemic infection that can quickly lead to circulatory shock, organ failure and death if inappropriately treated. In 2017, over 2 million people were admitted to US hospitals for sepsis (#1 cause of index admissions) at a total aggregate cost to the US healthcare system of $38.2 billion dollars (#1 most expensive condition), according to an AHRQ report. Over 270,000 people die of sepsis in the US every year, more than from prostate cancer, breast cancer and AIDS combined. Despite its large toll on public health, public awareness of this condition is poor and the quality of treatment is highly variable often due to delayed recognition and treatment. In sepsis, time is of the essence. Successful treatment hinges on prompt recognition of symptoms, correct antibiotic administration, and hemodynamic stabilization. Lack of appropriate sepsis management knowledge at the bedside leads to delayed symptom recognition, serious complications, medical errors, increased treatment costs, and avoidable morbidity and mortality. For this reason, we created this app to provide busy health professionals with essential management information based on the latest practice guidelines in a format that is easily accessible at the point of care. The Sepsis app was developed on the ESCAVO mobile publishing platform created specifically for mobile publishing of scientific content. The platform features an intuitive user interface, search, annotation and bookmarking functions, and calculator support. All content is extensively referenced and footnoted where appropriate. Clinical topics covered in the Sepsis app include: - Updated with the latest definitions, diagnostic criteria, and management guidelines including the 2016 Sepsis-3 definitions and the latest Surviving Sepsis Campaign (SSC) guidelines - Epidemiology, risk factors and pathophysiology of sepsis and septic shock - Common differentials and etiology, guidelines on performing appropriate H&P and workups - Management of common causes including hospital-acquired pneumonia (HAP), ventilator-acquired pneumonia (VAP) and intra-abdominal infections - Sepsis management bundles, early goal-directed therapy, hemodynamic management, adjunctive therapies, mechanical ventilation of sepsis-induced ARDS, and other essential management guidelines from the SSC and the American Thoracic Society (ATS) - Antibiotic therapy including specific guidelines for the treatment of HAP from ATS and the Infectious Diseases Society of America (IDSA) - Guidance on the prevention, recognition and treatment of Clostridium difficile based on the latest IDSA guidelines - Information on the diagnosis and management of pediatric and neonatal sepsis including the management of pediatric fever, important differences from adult sepsis, management of sepsis-induced persistent pulmonary hypertension of the newborn (PPHN), empiric antibiotic treatment recommendations for GBS infections, interventions in pediatric septic shock, and other pediatric-specific information - Important score calculators including the Sequential Organ Failure Assessment (SOFA), quick-SOFA, SIRS, APACHE II, Multiple Organ Dysfunction Score (MODS), the Simplified Acute Physiology Score (SAPS) II, National Early Warning Score (NEWS), the Clinical Pulmonary Infection (CPI) score, the Inferior Vena Cava Collapsibility Index, and others - Drug administration information for the management of sepsis including antibacterial and antifungal antibiotics, the latest drugs for emerging multi-drug resistant organisms, adrenergic and other vasoactive agents, corticosteroids and diuretics - Relevant COVID-19 management information Recommended by: - HealthTap.com - MDLinx.com - imedicalapps.com - The ED Trauma Critical Care Blog (edtcc.com)

About

Safe Vent

Read full description

Safe Vent performs calculations and provides recommendations designed to guide and complement healthcare team decisions in anesthesia/operating rooms, emergencies, and intensive care units. Oxygenation formulas, ventilation, mechanical power, driving pressure, and optimal PEEP predicted by Artificial Intelligence are some of its interesting features. This application does not replace individualized medical judgment for each patient and specific situation. Privacy policy: https://docs.google.com/document/d/1ESNGzHMyY034zsNM9J1f7BLyS47zP1PTvdaTCp1sdfg/edit?pli=1#heading=h.2gfsp4psfhxd Terms and Conditions: https://www.apple.com/legal/internet-services/itunes/dev/stdeula/

Screenshots

Sepsis Clinical Guide4 screens
Safe Vent2 screens

Verdict

The call

The clearest difference is in-app purchases: Sepsis Clinical Guide at none against Safe Vent's 2. On price, update cadence, ads and device support there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. Safe Vent sells 2 in-app purchases, starting at $2.99 per month. Sepsis Clinical Guide asks for nothing beyond the download.

UpkeepUpdate frequency

Sepsis Clinical Guide ships an update every 4 months, Safe Vent every 3 months. The most recent releases landed on October 29, 2026 and October 27, 2026 respectively.

Scorecard1 real difference · 9 level
Sepsis Clinical Guide versus Safe Vent: the parameters behind the verdict, then further details
ParameterSepsis Clinical GuideSafe Vent
PriceFreeFree
Rating4.8 (304 ratings) — better—
Positive reviews94.4% of reviews—
Number of ratings304 — better—
Update frequencyEvery 4 monthsEvery 3 months — better
AdsNoNo
In-app purchasesNo — betterYes
MonetizationFree—
DevicesiPhone, iPad, iPodiPhone, iPad, iPod
Requires iOS12.0 — better13.0
Further details — not scored
Size139 MB58 MB
Age rating17+17+
DeveloperEscavo, IncSYNAPS AI SAS

Bugs and requests

Sepsis Clinical Guide

Reported bugs

1 issue
  • App freezes on initial update and won't open

Requested features

1 request
  • Ideal body weight chart and formula

Safe Vent

Not enough reviews yet to summarise bugs or requests.

In-app purchases

None

Sepsis Clinical Guide

No in-app purchases

2 purchases

Safe Vent

Subscriptions2
  • Safe Vent Full Access3 Days trial$2.991 Month
  • Safe Vent Full Access3 Days trial$29.991 Year

Questions

Is Sepsis Clinical Guide free?
Sepsis Clinical Guide is free to download, with no in-app purchases.
Is Safe Vent free?
Safe Vent is free to download, with in-app purchases available.
Do Sepsis Clinical Guide or Safe Vent have ads?
Neither Sepsis Clinical Guide nor Safe Vent shows ads.
Which is updated more often, Sepsis Clinical Guide or Safe Vent?
Sepsis Clinical Guide ships an update every 4 months, and Safe Vent every 3 months. Most recently, Sepsis Clinical Guide was updated on October 29, 2026 and Safe Vent on October 27, 2026.

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