Comparison

ApoThera vs Mosby's Drug Reference

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

ApoThera

This app provides clinical decision support for healthcare professionals. It offers treatment recommendations, disease management tools, drug information, interaction checkers, medical calculators, and patient savings programs. Content is updated daily and covers a wide range of medical specialties.

Highlights
  • Clinical guidelines and treatment recommendations
  • Disease management and drug information
  • Drug interaction checker
  • Medical calculators and conversion tools
  • Patient Rx savings and discounts
  • PDF document archiving
Features
Read full description

ApoThera - Clinical Decision Support - Mobile Application ApoThera - features the following seven medical applications: 1) Clinical Guidelines • Treatment recommendations provided by peer-reviewed journals and manufacturers based on evidence-based medicine to optimize patient care 2) Disease Management • Providing treatment options for thousands of diseases and conditions based on manufacturers drug database provided by pharmaceutical manufacturers. 3) Drug Information • Providing drug information and medical reference for thousands of FDA-approved brand, generic, and OTC medicines based on drug database provided by pharmaceutical manufacturers. • Search by brand, generic or pharmacologic class names. • Drug monographs updated continuously with the latest information. 4) Drug Interaction Checker • Providing mutli-drugs interaction check with accurate clinical answers for any possible drug-drug interactions at the point of care with detail information about onset, severity warning management, mechanism, and references for all FDA-approved mechanisms. 5) ApoThera Medical Calculators & Conversion Tools • Processing clinical algorithms, calculating medical scores, scales, classifications • Cardiovascular Conversion Tool - Beta-Blockers Conversion Tool - ACE Inhibitors Conversion Tool - Angiotensins Receptor Blockers (ARBs) Conversion Tool - HMG-CoA Reductase Inhibitors (Statins) Conversion Tool - Diuretics Conversion Tool - Vasodilators Conversion Tool • Endocrinology Conversion Tool - Antidiabetics Conversion Tool - Insulin Conversion Tool - Thyroids Conversion Tool - Epoetin alfa Conversion Tool • Opioids Conversion Tool • Corticosteroids Conversion Tool • Benzodiazepines Conversion Tool • Psychoneurology Conversion Tool - Antipsychotics Conversion Tool - Antidepressants Conversion Tool - Antiepileptics Conversion Tool • Gastroenterology Conversion Tool - Proton Pump Inhibitors (PPIs) Conversion - H2 Blockers Conversion Tool • Total Parenteral Nutrition 6) PDF Box • Uploading and archiving PDF documents. 7) Patient Rx Savings • Discounts and coupons available through manufacturers for expensive biotechnology specialty medications. Medical Specialties: Anesthesiology, Cardiology & Vascular Medicine, Critical Care & Emergency Medicine, Endocrinology, Gastroenterology, Geriatric Medicine, Hematology - Oncology, Infectious Disease, Internal Medicine, Neurology, Obstetrics & Gynecology, Orthopedics, Pediatric, Psychiatric, Pulmonary Medicine, Surgery, Toxicology and Urology. • ApoThera content is updated daily.• ApoThera Premium monthly auto-renewable subscription allows full access to all calculation tools for 1 month. Payment will be charged to the user's iTunes Account at confirmation of purchase. After successful purchase, all disabled calculation tools and drug info will become active. After exactly 1 month from the subscription purchase date, the monthly subscription will renew automatically for another month at the subscription price on the date of the renewal. To cancel auto renewal, users must turn off the auto-renewal 24 hours before the renewal date by going to their iTunes account settings. Any unused portion of a free trial period will be forfeited when the user purchases a subscription. For ApoThera End User License Agreement, please visit: http://www.apothera.com/WS/GetAppInfo.aspx?Type=1

About

Mosby's Drug Reference

This app provides healthcare professionals with comprehensive drug information, including actions, usage, dosage, interactions, and side effects. It emphasizes patient safety with Black Box Warnings, Safety Alerts, and information on life-threatening side effects. Features include custom notes, highlights, and quick search functionality.

Highlights
  • Over 5,000 drug listings
  • Black Box Warnings and Safety Alerts
  • Drug action, usage, dosage, interactions, side effects
  • Custom notes and highlights
  • Full text search
  • Appendix of recent FDA-approvals
Features
Currently charting
Read full description

14-Day Free Trial ** Trusted by Health Care Professionals for Over 30 Years ** ABOUT MOSBY’S DRUG REFERENCE Based on the latest edition, Mosby's Drug Reference provides health care professionals with the tools they need to eliminate errors and improve accuracy. Drug monographs feature concise, easy-to-understand information and make finding answers easy with sections on each drug's action, usage, dosage, interactions, side effects, and more. With an emphasis on patient safety, this best-selling app includes Black Box Warnings for dangerous adverse reactions, Safety Alerts for situations requiring special attention, and a focus on life-threatening side effects of 50 common drug classes. FEATURES • More than 5,000 generic and trade-name drugs are profiled • Appendix of recent FDA-approvals • Icons for High Alert and Rarely Used medications • Highlighted Black Box Warnings, safety alerts, and life-threatening side effects • Helpful IV therapy updates • Create custom notes and highlights within entries • 150+ abbreviations listed for practical understanding • Unlabeled uses and help with easily confused drug names • Full Text Search helps find medications quickly • “Favorites” for bookmarking important entries FREE 14-DAY TRIAL: WHAT TO EXPECT • First-time users can access Unbound's complete Mosby's Drug Reference mobile app free for 14 days • After 14 days, your iTunes account will be charged $45.99 for a one-year subscription unless you have turned off auto-renew at least 24 hours before the free trial ends. • To manage your subscriptions, open Apple's “Settings” app and tap on the “iTunes & App Store" entry. Tap your Apple ID at the top of the screen and login. Tap subscriptions, then tap the subscription you wish to manage. •NOTE: If you choose not to purchase a subscription, content will no longer be viewable after the free trial period. iTunes automatic renewal: Your subscription automatically renews unless auto-renew is turned off 24 hours prior to the conclusion of your current period. Auto Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase. Your iTunes account will automatically be charged the current renewal rate ($45.99) within 24 hours prior to the end of the subscription period. If you choose not to renew, you will be able to use the app, however will not receive updates. Authors: Linda Skidmore-Roth, RN, MSN, NP Publisher: Elsevier Powered by: Unbound Medicine Unbound Privacy Policy: www.unboundmedicine.com/privacy Unbound Terms of Use: https://www.unboundmedicine.com/end_user_license_agreement

Screenshots

ApoThera4 screens
Mosby's Drug Reference4 screens

Verdict

The call

The clearest difference is review sentiment: ApoThera at 89% against Mosby's Drug Reference's 32%. ApoThera also leads on update cadence (every 2 months vs every 9 months) and iOS requirement (11.0 vs 15.0). Mosby's Drug Reference's advantage is ads (none vs shown) and rating (4.6 vs 4.2). On price, in-app purchases, monetization model and device support there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. ApoThera sells 2 in-app purchases, starting at $2.99 per month and Mosby's Drug Reference sells 1 in-app purchase, starting at $45.99 per year. Whichever you choose, the download price is not the number that matters.

ReceptionRating · Positive reviews · Number of ratings

Mosby's Drug Reference holds the better App Store score, 4.6 against 4.2. That said, the two scores are not equally well evidenced: Mosby's Drug Reference has 235 ratings behind it against 14, so its average is the more settled of the two. Written reviews complicate that: 89% of ApoThera's written reviews are positive against 32% of Mosby's Drug Reference's, so the app with the better star average is not the one people write more warmly about.

UpkeepUpdate frequency

ApoThera ships an update every 2 months, Mosby's Drug Reference every 9 months. The most recent releases landed on October 8, 2026 and October 15, 2026 respectively.

Scorecard7 real differences · 4 level
ApoThera versus Mosby's Drug Reference: the parameters behind the verdict, then further details
ParameterApoTheraMosby's Drug Reference
PriceFreeFree
Rating4.2 (14 ratings)4.6 (235 ratings) — better
Positive reviews88.9% of reviews — better31.8% of reviews
Number of ratings14235 — better
Update frequencyEvery 2 months — betterEvery 9 months
AdsYesNo — better
In-app purchasesYesYes
MonetizationFree with in-app purchasesFree with in-app purchases
Best chart rank—#200 — better
DevicesiPhone, iPad, iPodiPhone, iPad, iPod, Mac — better
Requires iOS11.0 — better15.0
Further details — not scored
Size19 MB9 MB
Age rating17+17+
DeveloperApothera Inc.Unbound Medicine, Inc.

Customer experience

ApoThera

All ratings14 ratings
Positive78.6%
Neutral0.0%
Negative21.4%
Written reviews27 reviews
Positive88.9%
Neutral0.0%
Negative11.1%

Mosby's Drug Reference

All ratings235 ratings
Positive88.9%
Neutral3.4%
Negative7.7%
Written reviews22 reviews
Positive31.8%
Neutral9.1%
Negative59.1%

In-app purchases

2 purchases

ApoThera

Subscriptions2
  • ApoThera Monthly$2.991 Month
  • ApoThera 1 year Auto-Renew7 Days trial$59.991 Year
1 purchases

Mosby's Drug Reference

Subscriptions1
  • Mosby's Drug Reference14 Days trial$45.991 Year

Questions

Is ApoThera free?
ApoThera is free to download, with in-app purchases available.
Is Mosby's Drug Reference free?
Mosby's Drug Reference is free to download, with in-app purchases available.
Which has better reviews, ApoThera or Mosby's Drug Reference?
Mosby's Drug Reference is rated higher. ApoThera averages 4.2 out of 5 from 14 ratings, while Mosby's Drug Reference averages 4.6 from 235 ratings.
Do ApoThera or Mosby's Drug Reference have ads?
ApoThera shows ads; Mosby's Drug Reference does not.
Which is updated more often, ApoThera or Mosby's Drug Reference?
ApoThera ships an update every 2 months, and Mosby's Drug Reference every 9 months. Most recently, ApoThera was updated on October 8, 2026 and Mosby's Drug Reference on October 15, 2026.

Other comparisons