Best Disease Apps & Games

246+ iOS apps & games curated and reviewed

4.5 avg rating
18 free apps & games
Updated November 2026

Looking for free disease apps and games? 18 of our 246+ tracked titles are free to download โ€” no subscription, no trial. The rest are premium picks worth paying for.

Compare top Disease Apps & Games (November 2026)

#AppPriceRatingAdsIn-App PurchasesUpdated
1Plague Inc.Plague Inc.$0.994.8โ˜… (168K)NoYesNov 2026
2Infection Bio WarInfection Bio WarFree4.6โ˜… (20K)NoYesNov 2026
3Bio inc. RedemptionBio inc. RedemptionFree4.7โ˜… (2.2K)YesYesNov 2026
4Disease Guide..Disease Guide..Freeโ€”YesYesOct 2026
5ECG & Disease TreatmentECG & Disease TreatmentFreeโ€”NoYesMay 2026
6Disease Dictionary - Disease ListDisease Dictionary - Disease ListFreeโ€”NoNoMay 2026
7Diseases and drugs finderDiseases and drugs finderFreeโ€”NoNoMay 2026
8Orthopaedics - Understanding DiseaseOrthopaedics - Understanding DiseaseFreeโ€”NoYesNov 2026

Top Picks for Disease

Plague Inc.#1

Plague Inc. by Ndemic Creations

Can you Infect the World?
Editor's Choice
๐ŸŽฎ Games
4.8๐Ÿ˜Š(168K ratings)
$0.99In-App Purchases
#1in Games
Plague Inc. screenshot 1
Plague Inc. screenshot 2
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Plague Inc. screenshot 5
Plague Inc. screenshot 6

A strategic simulation game where you evolve a deadly pathogen to infect the world and end humanity. Adapt your plague against global defenses and master different disease types to achieve victory. It's a high-stakes battle of strategy against the entire planet.

What We Love

  • ๐Ÿš€ Addictive gameplay
  • ๐Ÿค” Challenging and thought-provoking
  • ๐Ÿ‘ Realistic disease simulation
  • ๐Ÿ’ก Unique scenarios and special disease types
  • ๐ŸŽจ Immersive graphics and audio

Room to Improve

  • ๐Ÿ’ฐ Expensive in-app purchases
  • ๐Ÿ•ฐ๏ธ Slow progression without paying
  • ๐Ÿ› Inconsistent game mechanics
  • ๐Ÿค– Unrealistic cure development
  • ๐Ÿค” Lack of multiplayer mode
Infection Bio War#2

Infection Bio War by Wildlife Studios

Spread the Plague!
Strong Contender
๐ŸŽฎ Games
4.6๐Ÿ˜Š(20K ratings)
FreeIn-App Purchases
Infection Bio War screenshot 1
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Infection Bio War screenshot 5

A strategy game where you infect the global population with a custom disease. Evolve your pathogen with various transmission methods, symptoms, and resistances to achieve world domination.

What We Love

  • ๐Ÿ‘ Decent for a free app
  • ๐Ÿ‘ Fun and addictive
  • ๐Ÿ‘ Pretty great with a winning strategy
  • ๐Ÿ‘ Great game, one small issue
  • ๐Ÿ‘ Entertaining but way easy
  • ๐Ÿ‘ Addicting as heck
  • ๐Ÿ‘ Amazing game, one small issue
  • ๐Ÿ‘ Really good game
  • ๐Ÿ‘ Awesome substitute, but some kinks
  • ๐Ÿ‘ Really Fun
  • ๐Ÿ‘ Great game, but one small issue
  • ๐Ÿ‘ Addictive could be updated
  • ๐Ÿ‘ Highly Recommend But One Problem
  • ๐Ÿ‘ Great game
  • ๐Ÿ‘ Amazing
  • ๐Ÿ‘ Awesome game
  • ๐Ÿ‘ AMAZING GAME

Room to Improve

  • ๐Ÿ› Certain African countries won't grow
  • ๐Ÿ› Worm gamemode has a bug
  • ๐Ÿ› Scrolling issues
  • ๐Ÿ› Unlocking features can be difficult
  • ๐Ÿ› Game becomes too easy
  • ๐Ÿ› Lack of new content and updates
  • ๐Ÿ› Unbalanced gameplay mechanics
  • ๐Ÿ› Uninspired and low-effort
  • ๐Ÿ› Rigged to make you lose
  • ๐Ÿ› Slow scrolling
  • ๐Ÿ› Game gets boring over time
  • ๐Ÿ› Terrible UI and user experience
  • ๐Ÿ› Plagiarism of Plague Inc.
Bio inc. Redemption#3

Bio inc. Redemption by DryGin Studios

Medical & Doctor Simulation
Worth Considering
๐ŸŽฎ Games
4.7๐Ÿ˜(2.2K ratings)
FreeAdsIn-App Purchases
Bio inc. Redemption screenshot 1
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Engage in a complex biomedical simulation where you can either create deadly illnesses to infect victims or lead a medical team to find cures. Explore two distinct campaigns, develop strategies, and compete in world tournaments. The game offers realistic medical scenarios with a focus on strategic decision-making.

What We Love

  • ๐Ÿ‘ Fun and interesting gameplay
  • ๐Ÿš€ Realistic and challenging
  • ๐Ÿ’ก Ability to choose between saving or killing the patient
  • ๐Ÿ‘ Teaches about diseases and medicine

Room to Improve

  • ๐Ÿ› Frequent crashes and freezes
  • ๐Ÿ› Issues with energy/coin system and power-ups
  • ๐Ÿ› Bugs with completing levels and earning rewards
  • ๐Ÿ› Loading problems and unresponsive app

More Disease apps to explore

FAQ about Disease

What are the best disease apps & games for iPhone?
Plague Inc. tops our disease apps & games ranking as of November 2026, with a 4.8-star average from 168K App Store ratings, and it's priced at $0.99.
Yes โ€” 18 of the top disease apps & games we rank are free to download, including Infection Bio War and Bio inc. Redemption.
Plague Inc. has no ads and offers in-app purchases, according to its App Store listing as of November 2026.
We track 246+ disease apps & games on the iOS App Store as of November 2026, ranked by rating, recency, and analysis of real user reviews.

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