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Best The Plague Apps & Games

193+ iOS apps & games curated and reviewed

4.5 avg rating
18 free apps & games
Updated May 2026

Plague Inc. is the household name in the plague, but it's far from the only option. We track 193+ alternatives and competitors on iOS — many free, many higher-rated than you'd expect.

Compare top The Plague Apps & Games (May 2026)

#AppPriceRatingAdsIn-App PurchasesUpdated
1Plague Inc.Plague Inc.$0.994.8★ (166K)NoYesAug 2026
2Infection Bio WarInfection Bio WarFree4.6★ (20K)NoYesAug 2026
3Last Asylum: PlagueLast Asylum: PlagueFree4.8★ (33K)NoYesAug 2026
4Bio Inc. - Biomedical PlagueBio Inc. - Biomedical PlagueFree4.4★ (2.4K)NoYesAug 2026
5Zombie Outbreak SimulatorZombie Outbreak SimulatorFree4.1★ (1.6K)YesYesAug 2026
6Patient Zero: Virus gamePatient Zero: Virus gameFree4.6★ (4.1K)YesYesAug 2026
7Plague Inc: Scenario CreatorPlague Inc: Scenario Creator$2.994.4★ (1.1K)NoNoAug 2026
8Virus Plague: Survival WarsVirus Plague: Survival WarsFree4.6★ (30)YesYesAug 2026

Top Picks for The Plague

Plague Inc.#1

Plague Inc. by Ndemic Creations

Can you Infect the World?
Editor's Choice
🎮 Games
4.8😊(166K ratings)
$0.99In-App Purchases
#2in Games
Plague Inc. screenshot 1
Plague Inc. screenshot 2
Plague Inc. screenshot 3
Plague Inc. screenshot 4
Plague Inc. screenshot 5
Plague Inc. screenshot 6

A strategic simulation game where you evolve a deadly pathogen to infect the world and end humanity. Adapt your plague against global defenses and master different disease types to achieve victory. It's a high-stakes battle of strategy against the entire planet.

What We Love

  • 🚀 Addictive gameplay
  • 🤔 Challenging and thought-provoking
  • 👍 Realistic disease simulation
  • 💡 Unique scenarios and special disease types

Room to Improve

  • 💰 Expensive in-app purchases
  • 🕰️ Slow progression without paying
  • 🐛 Inconsistent game mechanics
Infection Bio War#2

Infection Bio War by Wildlife Studios

Spread the Plague!
Strong Contender
🎮 Games
4.6😊(20K ratings)
FreeIn-App Purchases
Infection Bio War screenshot 1
Infection Bio War screenshot 2
Infection Bio War screenshot 3
Infection Bio War screenshot 4
Infection Bio War screenshot 5

A strategy game where you infect the global population with a custom disease. Evolve your pathogen with various transmission methods, symptoms, and resistances to achieve world domination.

What We Love

  • 👍 Decent for a free app
  • 👍 Fun and addictive
  • 👍 Pretty great with a winning strategy
  • 👍 Great game, one small issue

Room to Improve

  • 🐛 Certain African countries won't grow
  • 🐛 Worm gamemode has a bug
  • 🐛 Scrolling issues

More The Plague apps to explore

4
Bio Inc. - Biomedical Plague
Bio Inc. - Biomedical Plague
Bio Inc. - Biomedical Plague
Diseases and infection RTS
Free

Develop lethal illnesses to determine a victim's fate in this biomedical strategy simulator. Upgrade diseases, boost risk factors, and slow recovery before doctors find a cure. Offers hours of gameplay with realistic conditions and numerous stages.

Biomedical strategy simulatorDevelop lethal illnessesUpgrade diseases and risk factors
🎮 Games
(2.4K)
free with in-app purchases
5
Zombie Outbreak Simulator
Zombie Outbreak Simulator
Zombie Outbreak Simulator
by Binary Space Pty Ltd
Free

Simulate and customize zombie outbreaks in real-world locations using Google Maps. Control outbreak parameters, observe chaos unfold, and even join the fight with military interventions. Explore thousands of player-created maps or offline options.

Real-world map simulation with Google Maps integrationCustomizable outbreak parameters (zombie speed, civilian numbers, etc.)Observe infection spread from satellite to street view
🎮 Games
(1.6K)
free with in-app purchases
6
Patient Zero: Virus game
Patient Zero: Virus game
Patient Zero: Virus game
Apocalypse simulator
Free

Simulate the creation and spread of a deadly plague in this realistic apocalypse simulator. Adapt your pathogen against global efforts to stop it and decide the fate of humanity. It's a strategic test of biology and survival.

Hyper-realistic virus simulationDevelop and adapt unique diseasesGlobal infection across all countries
🎮 Games
(4.1K)
free with in-app purchases
7
Plague Inc: Scenario Creator
Plague Inc: Scenario Creator
Plague Inc: Scenario Creator
by Ndemic Creations
$2.99

Design and share your own custom scenarios for a popular strategy game. Create unique plagues, worlds, and events, then unleash them on a global player base. Requires the original game to play created scenarios.

Create custom plague typesDesign unique worlds and country attributesDevelop government responses
🔧 Utilities
(1.1K)
free
8
Virus Plague: Survival Wars
Virus Plague: Survival Wars
Virus Plague: Survival Wars
World infection - Ways to Cure
Free

Lead the global effort to find a cure for a deadly infection unleashed by Dr. Plague. Strategically manage resources, upgrade abilities, and make critical decisions on a realistic world map to contain the outbreak and save humanity.

Fight the infectionRealistic world map trackingStrategic gameplay and decision-making
🎬 Entertainment
(30)
free with in-app purchases
9
BitLife - Life Simulator
BitLife - Life Simulator
BitLife - Life Simulator
Live your best (or worst) life
Free

Experience a text-based life simulator where every choice shapes your destiny. Build a dream life with love and career, or embrace chaos with crime and scandal. Your virtual life story unfolds with every decision.

Text-based life simulationChoice-driven roleplayingBuild a dream life
🎮 Games
(1.8M)
free with in-app purchases
10
Bio inc. Redemption
Bio inc. Redemption
Bio inc. Redemption
Medical & Doctor Simulation
Free

Engage in a complex biomedical simulation where you can either create deadly illnesses to infect victims or lead a medical team to find cures. Explore two distinct campaigns, develop strategies, and compete in world tournaments. The game offers realistic medical scenarios with a focus on strategic decision-making.

Biomedical simulationCreate illnesses or find curesRealistic diseases and conditions
🎮 Games
(2.2K)
free with in-app purchases
11
WorldBox - God Sandbox
WorldBox - God Sandbox
WorldBox - God Sandbox
Best world building simulator!
Free

Create and shape your own pixel worlds with this god simulation sandbox game. Spawn creatures, build civilizations, and unleash powerful disasters or creative tools to watch life evolve. Experiment with various powers and enjoy offline play.

Create and spawn creaturesBuild and evolve civilizationsSimulate natural disasters
🎮 Games
(77K)
free with in-app purchases
12
Cosmic Plague
Cosmic Plague
Cosmic Plague
Cosmic Plague
Free

Navigate nanobots through the human circulatory system to combat a global cosmic microorganism outbreak. Compete with others to achieve the highest score and become the world champion in this action-packed game.

Navigate nanobotsCombat cosmic microorganismsCompete for high scores
🎮 Games
(1)
ad-supported
13
Nano War - Cells VS Virus
Nano War - Cells VS Virus
Nano War - Cells VS Virus
Fight The Virus Online
Free

Engage in a real-time strategy game where you command immune cells to conquer infected territories. Plan your attacks, capture cell types, and save the human body from viruses. Challenge AI or up to three players online in epic battles.

Real-time strategy gameplayConquer infected territoriesCommand immune cells
🎮 Games
(53)
free
14
Infection of the dead
Infection of the dead
Infection of the dead
Action puzzle game
Free

Embody a zombie in this action-puzzle game. Grow your horde by turning humans into zombies, overwhelming crowds and overcoming stage-specific challenges. The goal is to infect a set number of people to clear each level.

Play as a zombieGrow your zombie hordeCrowd-based action
🎮 Games
(6.6K)
free with in-app purchases
15
Zombies vs Ninja
Zombies vs Ninja
Zombies vs Ninja
New master
Free

Engage in a thrilling zombie-slaying adventure as a ninja. Strategically shoot shurikens and bombs to defend your homeland from hordes of zombies and powerful bosses. Earn coins, unlock new weapons, and collect daily surprises to aid your fight.

Shoot shurikens and bombsDefeat various zombie typesBattle zombie bosses
🎮 Games
(546)
free with in-app purchases
16
Dead Spreading:Idle Game
Dead Spreading:Idle Game
Dead Spreading:Idle Game
Build and merge with strategy!
Free

Build and merge strategically to resist the undead. Recruit soldiers, upgrade your base, and fight off waves of enemies. Experience dynamic day/night cycles and weather for immersive battles.

Recruit and upgrade soldiersBuild and upgrade baseCollect Rage Serum
🎮 Games
(4.9K)
free with in-app purchases
17
Days After: Zombie Survival
Days After: Zombie Survival
Days After: Zombie Survival
Last Life on Earth: Apocalypse
Free

Survive a zombie apocalypse by crafting tools, building a base, and fighting off threats. Explore a desolate world, manage hunger and thirst, and uncover the story of the infection through quests and raids. Every moment is a fight for survival.

Resource collection and craftingBase constructionCombat against zombies and animals
🎮 Games
(17K)
free with in-app purchases
18
Dark War:Survival
Dark War:Survival
Dark War:Survival
by Omnilojo Pte Ltd
Free

Lead survivors in a post-apocalyptic world overrun by zombies. Build and expand your shelter, gather resources, recruit and train survivors, and form alliances to fight the undead and rebuild civilization.

Assign jobs to survivorsGather resources and explore wastelandsBuild and expand your shelter
🎮 Games
(64K)
free with in-app purchases
19
Fallout Shelter
Fallout Shelter
Fallout Shelter
Build Your Underground Vault
Free

Build and manage an underground vault in a post-apocalyptic world. Assign jobs, train dwellers, and send them on quests to explore the wasteland and gather resources. Protect your community from threats and expand your vault to ensure survival.

Build underground vault roomsManage and train dwellersExplore the wasteland on quests
🎮 Games
(562K)
free with in-app purchases
20
Zombie Gunship: Gun Down Zombies
Zombie Gunship: Gun Down Zombies
Zombie Gunship: Gun Down Zombies
by ZSpectre, Inc.
Free

Take control of an AC-130 gunship to defend survivors from relentless zombie hordes. Utilize powerful weaponry and night vision to strategically eliminate threats. Earn bounties to upgrade your arsenal and climb the leaderboards.

AC-130 gunner seat3D night vision displayAuthentic weapons (Gatling, Bofors, Howitzer)
🎮 Games
(34K)
free with in-app purchases

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FAQ about The Plague

What are the best the plague apps & games for iPhone?
Plague Inc. tops our the plague apps & games ranking as of May 2026, with a 4.8-star average from 166K App Store ratings, and it's priced at $0.99.
Yes — 18 of the top the plague apps & games we rank are free to download, including Infection Bio War and Last Asylum: Plague.
Plague Inc. has no ads and offers in-app purchases, according to its App Store listing as of May 2026.
We track 193+ the plague apps & games on the iOS App Store as of May 2026, ranked by rating, recency, and analysis of real user reviews.
Plague Inc. is a unique strategy simulation game where your goal is to evolve a deadly pathogen and infect the world, bringing about the end of human history. You must adapt your plague against everything humanity does to defend itself, making it a high-stakes battle of strategy.
The game features stunning retina graphics, a hyper-realistic world with advanced AI, and a comprehensive tutorial system. You can master 12 different disease types with unique strategies, infect over 50 countries, and evolve hundreds of traits. It also includes expansion updates like the Neurax Worm and Necroa Virus.