Comparison

CTCAE 5 Pro vs IOTOX Algorithm

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

CTCAE 5 Pro

This app helps review and take notes on CTCAE documents. It offers local data storage for privacy and premium features like version comparison and advanced note-taking with a subscription.

Highlights
  • Streamlined CTCAE Document Access
  • Local data storage for enhanced privacy
  • Version comparison tool
  • Advanced chronological note-taking with hashtags
  • Custom app creation from spreadsheets
  • Flexible backup and archiving (XLSX, CSV)
Features
Read full description

CTCAE 5 Pro is designed to assist in the documentation, review, and reference of CTCAE-related information. This app is intended for informational support and is not designed for medical purposes such as diagnosis, clinical decision-making, or treatment recommendations. Users are responsible for verifying all information and making clinical decisions. ::::::::: Standard features (available to all users) :::::: - Streamlined CTCAE Document Access - Easily navigate CTCAE 5.0 documents using an intuitive interface. - Enhanced privacy with local data storage - protect your data by storing it locally instead of relying on cloud services, ensuring privacy and control. ::::::::: Premium Features (available with subscription) ::::::: - Version Comparison Tool - Easily compare different versions of CTCAE 5.0 and 4.03. - Advanced Notes feature - allows you to record CTCAEs in chronological order. You can also use hashtags and other features to efficiently organize and track notes for important information. - Custom App Creation Feature - Simply import a spreadsheet and convert it into a list app. No programming knowledge is required. - Flexible backup and archiving solution - easily back up and archive data in formats such as XLSX and CSV for versatility and accessibility. - More features are available in the Premium version. Note: With the Premium feature, a minimal number of files are automatically stored in a secure iCloud Drive to resume link information between files. This can be turned off based on user preference.

About

IOTOX Algorithm

This app provides clinical management algorithms for evaluating, diagnosing, and treating toxicities associated with cancer immunotherapies. It guides physicians on best practices for managing side effects that can arise during cancer treatment.

Highlights
  • Clinical management algorithms
  • Evaluation of toxicities
  • Diagnosis of side effects
  • Treatment of immunotherapy toxicities
  • Best practices for patient care
Features
Read full description

Immunotherapies have become essential in treating advanced malignancies. However, immunotherapies can attack healthy cells, leading to toxicities or side effects. To address how to best treat patients with these toxicities, the Internal Medicine division has collaborated with the Cancer Medicine division, as well as other divisions at MD Anderson, to create the Immuno-Oncology Toxicity (IOTOX) Leaders Group. ​​​​​​​ Clinical management algorithms depict best practices for evaluating, diagnosing, and treating specific conditions that arise during the course of cancer treatment. These algorithms are not intended to replace the independent medical judgment of the physician in the context of individual clinical circumstances to determine a patient's care.

Screenshots

CTCAE 5 Pro4 screens
IOTOX Algorithm4 screens

Verdict

The call

The clearest difference is in-app purchases: IOTOX Algorithm at none against CTCAE 5 Pro's 2. CTCAE 5 Pro's advantage is ratings volume (41 vs 1) and device support (3 vs 1). On price, rating, update cadence and ads there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. CTCAE 5 Pro sells 2 in-app purchases, starting at $1.99 per month. IOTOX Algorithm asks for nothing beyond the download.

ReceptionRating · Positive reviews · Number of ratings

On the App Store both sit at effectively the same score — 4.9 for CTCAE 5 Pro against 5.0 for IOTOX Algorithm. That said, the two scores are not equally well evidenced: CTCAE 5 Pro has 41 ratings behind it against 1, so its average is the more settled of the two.

UpkeepUpdate frequency

CTCAE 5 Pro ships an update every 5 weeks, IOTOX Algorithm every 6 weeks. The most recent releases landed on October 27, 2026 and October 22, 2026 respectively.

Scorecard5 real differences · 5 level
CTCAE 5 Pro versus IOTOX Algorithm: the parameters behind the verdict, then further details
ParameterCTCAE 5 ProIOTOX Algorithm
PriceFreeFree
Rating4.9 (41 ratings)5.0 (1 ratings) — better
Positive reviews0.0% of reviews—
Number of ratings41 — better1
Update frequencyEvery 5 weeks — betterEvery 6 weeks
AdsNoNo
In-app purchasesYesNo — better
MonetizationFreemiumFree — better
DevicesiPhone, iPad, iPod — betteriPhone
Requires iOS15.5 — better18.0
Further details — not scored
Size60 MB7 MB
Age rating17+17+
DeveloperKoichiro WatanabeMD Anderson Cancer Center

Customer experience

CTCAE 5 Pro

All ratings41 ratings
Positive97.6%
Neutral0.0%
Negative2.4%
Written reviews1 reviews
Positive0.0%
Neutral0.0%
Negative100.0%

IOTOX Algorithm

All ratings1 ratings
Positive100.0%
Neutral0.0%
Negative0.0%

In-app purchases

2 purchases

CTCAE 5 Pro

Subscriptions2
  • Monthly subscription7 Days trial$1.991 Month
  • Annual subscription7 Days trial$9.991 Year
None

IOTOX Algorithm

No in-app purchases

Questions

Is CTCAE 5 Pro free?
CTCAE 5 Pro is free to download, with in-app purchases available.
Is IOTOX Algorithm free?
IOTOX Algorithm is free to download, with no in-app purchases.
Which has better reviews, CTCAE 5 Pro or IOTOX Algorithm?
IOTOX Algorithm is rated higher. CTCAE 5 Pro averages 4.9 out of 5 from 41 ratings, while IOTOX Algorithm averages 5.0 from 1 ratings.
Do CTCAE 5 Pro or IOTOX Algorithm have ads?
Neither CTCAE 5 Pro nor IOTOX Algorithm shows ads.
Which is updated more often, CTCAE 5 Pro or IOTOX Algorithm?
CTCAE 5 Pro ships an update every 5 weeks, and IOTOX Algorithm every 6 weeks. Most recently, CTCAE 5 Pro was updated on October 27, 2026 and IOTOX Algorithm on October 22, 2026.

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