Milligram vs Substrato
Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.
Milligram
Optimize your health and performance with science-backed data. Track peptide levels, analyze bloodwork, and monitor progress with intelligent insights. Get personalized feedback on your protocol and health metrics.
- Intelligent protocol analysis
- Compound level tracking
- Bloodwork analysis and biomarker flagging
- Comprehensive compound library
- Progress scans for body composition
- Stack analytics and interaction flagging
- Journaling for health metrics
- Reconstitution calculator
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Whether you're optimizing for fat loss, muscle gain, longevity, recovery or anti aging, Milligram is for people who want to take back control of their health protocols with science-backed confidence. Every other tracker gives you a tidier place to write down what you already did. Milligram models what is actually in your system right now. Every dose charted against every half-life. Everything in the stack with info and the database covering over 3,581 references total. Bloodwork read against what you are actually running. And an AI assistant that answers from your real-time numbers, read against a database made specifically for your protocol, not everyday questions. FEATURES Your Protocol: Everything you run, on one screen. Each compound with its own schedule, dose, vial and supply tracked, and the whole protocol read as one picture rather than being scattered across different notes, files and spreadsheets. Dose tracking: Log every dose, whether that's an injectable or an oral supplement - Milligram works with every compound and every dosing route. Reminders arrive on the protocol's schedule and know which compound, which dose and which injection site. Reconstitution Calculator: Mix any vial, any concentration. Convert mg, mcg, IU, and units for compound preparation. Designed for accurately mixing peptide vials with bacteriostatic water - saved to your compounds for quick reference. Milligram Intelligence: An assistant that already has your stack, your doses, your bloodwork and your Apple Health data loaded. Ask "what do I draw for 5mg from a 10mg vial in 2ml", "how is my weight tracking against my retatrutide cycle", or "did my IGF-1 move on tesamorelin", and get an answer from your own numbers. Level Buildup: See your compound levels build from each trough to peak. Every dose is charted against the published half-life of your compound, so you know exactly when you've reached the right zone at the right titration, how each dose is keeping you there, and how much a missed dose can actually move the needle. Bloodwork: Upload a PDF or a photo of your labs. Every biomarker is extracted and out-of-range values flagged, then kept where they can be read against the compounds that might be moving them. Compound Library: 202 compounds with mechanisms, dose ranges, half-lives, expected timelines and side-effect profiles, each referenced to clinical sources. Retatrutide, tirzepatide and semaglutide. Testosterone esters, Masteron, Anavar. Tesamorelin, BPC-157, GHK-Cu, MK-677, Ipamorelin and CJC-1295. Creatine, Omega-3 Fish Oil, Magnesium, Zinc, Vitamin D3, and more. AI calorie and nutrition tracking: Scan any meal with your camera. Snap a photo, scan a barcode, or scan a nutrition label and Milligram extracts calories, protein, carbs and fat instantly. Track every meal against your daily targets with a clean macro breakdown. Apple Health: Two-way sync for sleep, HRV, vitals, activity, weight and body composition, so protocol data and health data sit in the same timeline. SUBSCRIPTION AND TERMS Milligram Pro is accessible via an auto-renewing subscription. You may switch off auto-renew in your Apple ID Account Settings. Purchases of subscriptions will be charged using your Apple ID upon confirmation of purchase. Subscriptions renew on a monthly or yearly basis, unless canceled at least 24 hours before the end of the current period. If canceled, subscriptions remain valid until the end of the current period, and any unused portions are not valid for a refund. By signing in with Apple or by purchasing a subscription, you affirm your understanding of the following: Terms of Service: https://milligram.health/terms Privacy Policy: https://milligram.health/privacy Milligram is not a medical device and is not intended to diagnose, treat, cure, monitor, or prevent medical conditions or illnesses. Always consult your physician first. All information provided is for general informational purposes only.
Substrato
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Precision nutrition, without the spreadsheets. Substrato is a meal-planning app for people who take nutrition seriously — and for the coaches who program for them. Set macro targets over a dated protocol. Build meals from a real ingredient library. Cook once for the week, and portion every container with the exact math to hit your numbers. PLAN AND PREP YOUR WEEK • Dated protocols (cut, bulk, recomposition) with real start and end dates • Optional Training vs Rest day macros inside a single protocol • Prep: how much of each ingredient you need for the days ahead, with shelf-life warnings — then weigh a cooked batch once and portion it perfectly across every meal • Tag cooking methods for each ingredient (grilled, boiled, roasted…) so meal cards read at a glance • Meal logging: log what you actually ate and see how it lines up with the plan • Activity timeline: every protocol, evaluation, and logged meal in one place • Cloud sync for all your protocols, not just the active one TRAINER MODE Substrato Trainer turns your programming into a professional tool your athletes can execute with precision. • Manage every athlete on one screen • Build each athlete's protocol individually — personalized, not broadcast • Log caliper skinfold readings and body-composition data for each athlete — Substrato does the body-fat math and tracks progress between sessions • See each athlete's adherence through the meals they log in the Activity timeline • Athletes receive plans instantly and execute them with the same Prep tools you use Send in seconds. You keep a read-only copy. Athlete data stays private. TRUSTED DATA Nutrition values are sourced from public food-composition databases including the U.S. Department of Agriculture FoodData Central. Dietary guidance references the USDA Dietary Guidelines for Americans and the World Health Organization Healthy Diet fact sheet. Substrato provides nutritional information for meal planning and is not medical advice. WHY SUBSTRATO • Meal planning and Prep work offline • Coach handoffs, adherence tracking, and cross-device sync require an internet connection • Available in English, Spanish, Portuguese, Russian, and Simplified Chinese • Designed exclusively for iPhone
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Verdict
The clearest difference is update cadence: Milligram at every 4 days against Substrato's every 2 weeks. On price, ads, in-app purchases and device support there is nothing between them.
Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS
Both are free to download. Milligram sells 3 in-app purchases, starting at $17.49 per month and Substrato sells 5 in-app purchases, starting at $4.99 per month. Whichever you choose, the download price is not the number that matters.
Milligram ships an update every 4 days, Substrato every 2 weeks. The most recent releases landed on October 12, 2026 and October 5, 2026 respectively.
| Parameter | Milligram | Substrato |
|---|---|---|
| Price | Free | Free |
| Rating | 4.7 (313 ratings) — better | — |
| Positive reviews | 68.6% of reviews | — |
| Number of ratings | 313 — better | — |
| Update frequency | Every 4 days — better | Every 2 weeks |
| Ads | No | No |
| In-app purchases | Yes | Yes |
| Monetization | Free with in-app purchases | — |
| Devices | iPhone, Apple Watch — better | iPhone |
| Requires iOS | 17.0 — better | 17.6 |
| Further details — not scored | ||
| Size | 169 MB | 16 MB |
| Age rating | 12+ | 4+ |
| Developer | Enzo Anderson | Cristian Garske |
In-app purchases
Milligram
- Milligram Pro2 variants$17.491 Month
- Milligram Pro3 Days trial$49.991 Year
- Milligram Pro3 Days trial$69.991 Year
Substrato
- Premium$4.991 Month
- Trainer$14.991 Month
- Premium$39.991 Year
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- Trainer$119.991 Year
- Premium Lifetime$79.99









