Best Disease Simulation Apps & Games

0+ iOS apps & games curated and reviewed

4.6 avg rating
18 free apps & games
Updated June 2026

Every iPhone needs a few good disease simulation apps and games. We benchmark 0+ of them on App Store rating, freshness, and pricing, then surface the standouts so you don't have to scroll the App Store yourself.

Compare top Disease Simulation Apps & Games (June 2026)

#AppPriceRatingAdsIn-App PurchasesUpdated
1Plague Inc.Plague Inc.$0.994.8★ (167K)NoYesOct 2026
2Eye Disease SimulatorEye Disease SimulatorFree—NoNoSep 2026
3Bio inc. RedemptionBio inc. RedemptionFree4.7★ (2.2K)YesYesOct 2026
4Bio Inc. - Biomedical PlagueBio Inc. - Biomedical PlagueFree4.4★ (2.4K)NoYesOct 2026
5Patient Zero: Virus gamePatient Zero: Virus gameFree4.6★ (4.4K)YesYesOct 2026
6Infection Bio WarInfection Bio WarFree4.6★ (20K)NoYesOct 2026
7Full Code Medical SimulationFull Code Medical SimulationFree4.8★ (6.3K)NoYesOct 2026
8Dream Hospital: Medical TycoonDream Hospital: Medical TycoonFree4.4★ (4.1K)YesYesOct 2026

Top Picks for Disease Simulation

Plague Inc.#1

Plague Inc. by Ndemic Creations

Can you Infect the World?
Editor's Choice
🎮 Games
4.8😊(167K ratings)
$0.99In-App Purchases
#1in Games
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A strategic simulation game where you evolve a deadly pathogen to infect the world and end humanity. Adapt your plague against global defenses and master different disease types to achieve victory. It's a high-stakes battle of strategy against the entire planet.

What We Love

  • 🚀 Addictive gameplay
  • 🤔 Challenging and thought-provoking
  • 👍 Realistic disease simulation
  • 💡 Unique scenarios and special disease types
  • 🎨 Immersive graphics and audio

Room to Improve

  • 💰 Expensive in-app purchases
  • 🕰️ Slow progression without paying
  • 🐛 Inconsistent game mechanics
  • 🤖 Unrealistic cure development
  • 🤔 Lack of multiplayer mode
Bio inc. Redemption#3

Bio inc. Redemption by DryGin Studios

Medical & Doctor Simulation
Worth Considering
🎮 Games
4.7😐(2.2K ratings)
FreeAdsIn-App Purchases
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Engage in a complex biomedical simulation where you can either create deadly illnesses to infect victims or lead a medical team to find cures. Explore two distinct campaigns, develop strategies, and compete in world tournaments. The game offers realistic medical scenarios with a focus on strategic decision-making.

What We Love

  • 👍 Fun and interesting gameplay
  • 🚀 Realistic and challenging
  • 💡 Ability to choose between saving or killing the patient
  • 👍 Teaches about diseases and medicine

Room to Improve

  • 🐛 Frequent crashes and freezes
  • 🐛 Issues with energy/coin system and power-ups
  • 🐛 Bugs with completing levels and earning rewards
  • 🐛 Loading problems and unresponsive app

More Disease Simulation apps to explore

FAQ about Disease Simulation

What are the best disease simulation apps & games for iPhone?
Plague Inc. tops our disease simulation apps & games ranking as of June 2026, with a 4.8-star average from 167K App Store ratings, and it's priced at $0.99.
Yes — 18 of the top disease simulation apps & games we rank are free to download, including Eye Disease Simulator and Bio inc. Redemption.
Plague Inc. has no ads and offers in-app purchases, according to its App Store listing as of June 2026.