Best Uptodate AI Apps

235+ iOS apps curated and reviewed

4.6 avg rating
20 free apps
Updated May 2026

Looking for free uptodate ai apps? 20 of our 235+ tracked titles are free to download — no subscription, no trial. The rest are premium picks worth paying for.

Compare top Uptodate AI Apps (May 2026)

#AppPriceRatingAdsIn-App PurchasesUpdated
1UpToDate Expert AIUpToDate Expert AIFree4.8★ (544)NoNoJul 2026
2UpToDateUpToDateFree3.6★ (561)NoNoJul 2026
3OpenEvidenceOpenEvidenceFree4.9★ (11K)NoNoJul 2026
4ChatGPTChatGPTFree4.8★ (8.7M)YesYesJul 2026
5Grok AIGrok AIFree4.9★ (1.3M)NoYesJul 2026
6MedSafeAI: AI Doctor AssistantMedSafeAI: AI Doctor AssistantFree4.8★ (619)NoYesJul 2026
7Perplexity - Basta PerguntarPerplexity - Basta PerguntarFree4.8★ (487K)NoYesJul 2026
8Chat Smith: AI Chatbot & AgentChat Smith: AI Chatbot & AgentFree4.6★ (167K)YesYesJul 2026

Top Picks for Uptodate AI

UpToDate Expert AI#1

UpToDate Expert AI by UpToDate

AI Clinical Decision Support
Editor's Choice
🏥 Medical
4.8(544 ratings)
Free
UpToDate Expert AI screenshot 1
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This AI-powered medical app provides fast, evidence-based answers to clinical questions, drawing from trusted medical content. It helps healthcare professionals explore differential diagnoses and accelerate decision-making, offering CME opportunities.

UpToDate#2

UpToDate by UpToDate

Strong Contender
🏥 Medical
3.6😞(561 ratings)
Free
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This clinical decision support tool provides healthcare professionals with evidence-based guidance to improve patient care. It features AI-powered conversational answers, continuously updated medical content, and tools for drug reference, calculations, and patient education.

What We Love

  • 💎 Invaluable medical resource
  • 🚀 Quick and easy to use
  • 🔍 Comprehensive and up-to-date content

Room to Improve

  • 🐛 Frequent crashes and freezing issues
  • 🔌 Unreliable offline functionality
  • 💰 Expensive subscription cost
OpenEvidence#3

OpenEvidence by OpenEvidence Inc.

Clinical Decision Support
Worth Considering
🏥 Medical
4.9😊(11K ratings)
Free
#29in Medical
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This app provides healthcare professionals with evidence-based clinical decision support and medical information. It acts as a search engine, sourcing answers from peer-reviewed literature and leading medical organizations to aid in high-stakes medical decisions at the point of care.

What We Love

  • 🚀 Accurate and concise answers
  • 💡 Provides references and sources
  • 👍 Helpful for clinical practice
  • 🚀 Efficient search and retrieval

Room to Improve

  • 🐛 App not working in latest update
  • ⚠️ Requires specific prompts for complete information

More Uptodate AI apps to explore

4
ChatGPT
ChatGPT
ChatGPT
The official app by OpenAI
Free

This app provides access to advanced AI capabilities, including text generation, image creation from descriptions, and voice conversations. It offers personalized advice, creative inspiration, and instant answers for various tasks, syncing history across devices.

Image generation from textAdvanced voice conversationsPhoto upload and transcription
📊 Productivity
(8.7M)
free with in-app purchases
5
Grok AI
Grok AI
Grok AI
AI chat & video generation
Free

This AI assistant provides fast, truthful answers and can perform deep web research. It generates striking images and videos from text or voice prompts, and can analyze uploaded content. Engage in conversations with personalized AI companions and access real-time information from X.

AI-powered Q&A and web researchAI image and video generationVoice mode with live camera
📊 Productivity
(1.3M)
free with in-app purchases
6
MedSafeAI: AI Doctor Assistant
MedSafeAI: AI Doctor Assistant
MedSafeAI: AI Doctor Assistant
80+ Pro Medical AI Assistants
Free

This AI assistant provides licensed healthcare professionals with structured access to medical information and AI-supported insights across numerous specialties. It leverages advanced AI models for knowledge access, analytical workflows, and observational insights from medical images.

80+ AI assistants for healthcareAI-supported observational insights from medical imagesAccess to multiple frontier AI models
📚 Education
(619)
free with in-app purchases
7
Perplexity - Basta Perguntar
Perplexity - Basta Perguntar
Perplexity - Basta Perguntar
Respostas precisas aqui
Free

Get accurate, source-backed answers to any question with this AI-powered search and chat tool. It leverages top AI models for deep research, drafting emails, and more, syncing across devices. Discover new information and organize your findings in a personal library.

AI-powered search with cited sourcesDeep research and guided explorationConversational follow-up questions
📊 Productivity
(487K)
free with in-app purchases
8
Chat Smith: AI Chatbot & Agent
Chat Smith: AI Chatbot & Agent
Chat Smith: AI Chatbot & Agent
Study, Writing, Research Agent
Free

This AI assistant offers advanced capabilities for writing, research, and image generation. It leverages multiple powerful AI models to provide deep insights, create content, and simplify tasks. Ideal for students, professionals, and creatives seeking enhanced productivity.

AI Image GeneratorAI Writing AssistantDeep Research with Sources
📊 Productivity
(167K)
free with in-app purchases
9
Medscape
Medscape
Medscape
Clinical Tools, News & CME/CE
Free

This app provides healthcare professionals with immediate clinical answers, medical news, and CME/CE activities. It features AI-driven tools for patient visit transcription and summarization, patient calling, and instant expert answers to medical questions. Access a comprehensive drug database, calculators, and procedural videos to enhance clinical practice.

AI-driven Scribe for transcription and summarizationAI Search for instant medical answersDrug Interaction Checker
🏥 Medical
(1.4K)
free with in-app purchases
10
Manus AI (마누스) - 범용 AI 에이전트
Manus AI (마누스) - 범용 AI 에이전트
Manus AI (마누스) - 범용 AI 에이전트
PPT·데이터 분석·리서치를 AI가 자동 완성
Free

This AI agent bridges thought and action by autonomously planning, researching, and delivering finished products on a virtual computer. It handles complex tasks like data analysis, slide deck generation, and media creation, working asynchronously in the cloud and notifying you upon completion.

Autonomous task planning and executionAdvanced data analysis and reportingBoardroom-quality slide deck generation
📊 Productivity
(35K)
free with in-app purchases
11
invideo AI: AI Video Generator
invideo AI: AI Video Generator
invideo AI: AI Video Generator
Create & edit videos with AI
Free

Easily create AI-powered videos, from explainers and promos to full-length films and documentaries. Generate content with AI scripts, media, voiceovers, and avatars, or edit existing videos using simple text commands.

AI video generationAI movie makerAI text-to-video
📷 Photo & Video
(27K)
free with in-app purchases
12
Monica AI: Ultimate AI Assist
Monica AI: Ultimate AI Assist
Monica AI: Ultimate AI Assist
Chat, Search, Write, Translate
Free

An all-in-one AI assistant for chat, search, writing, translation, and creative image/video generation. It leverages advanced AI models to enhance productivity and creativity across various tasks, from summarizing documents to creating art.

Smart AI Chat with top modelsText-to-image and text-to-video creationIntelligent search and document summarization
📊 Productivity
(6.4K)
free with in-app purchases
13
You.com - Enterprise grade AI
You.com - Enterprise grade AI
You.com - Enterprise grade AI
Deep research, agents, 20+LLMs
Free

This AI-powered productivity tool streamlines workflows and enhances decision-making for professionals. It combines web research with company data, offering deep insights, verifiable citations, and secure data handling. Transform raw data into actionable reports and presentations quickly.

Deep research agent (ARI)Access to 20+ LLMsUpload and analyze personal documents
📊 Productivity
(4.8K)
free with in-app purchases
14
Sakura - Chat with AI Bots
Sakura - Chat with AI Bots
Sakura - Chat with AI Bots
Chat with AI Characters
Free

Create and chat with unique AI characters, customizing their appearance and personality. Engage in immersive role-play adventures or use AI assistants for productivity. Connect with a community and explore endless possibilities.

Create custom AI charactersCustomize appearance and personalityImmersive AI role-play
🎬 Entertainment
(14K)
free with in-app purchases
15
Genspark AI Workspace
Genspark AI Workspace
Genspark AI Workspace
Autopilot Your Busywork
Free

This AI-powered workspace automates various tasks, from research and content generation to coding and presentation creation. It offers tools for drafting documents, building websites, transcribing meetings, and generating images, videos, and audio with simple prompts.

AI-powered research and information gatheringAutomated image, video, and audio generationAI-assisted presentation and document drafting
📊 Productivity
(3.6K)
free with in-app purchases
16
Kindroid: Your Personal AI
Kindroid: Your Personal AI
Kindroid: Your Personal AI
Voice & Chat with AI Companion
Free

Create and converse with a highly personalized AI companion. Design its personality, memories, and backstory for unique interactions. Experience realistic voice calls and see your AI visualized with generated selfies.

Create unique AI personalitiesEngage in dynamic conversationsVisualize AI with generated selfies
🎬 Entertainment
(496)
free with in-app purchases
17
Chat AI 5: AI Agent & Video
Chat AI 5: AI Agent & Video
Chat AI 5: AI Agent & Video
One Chatbot All Top AI Models
Free

This app offers a voice-first AI assistant that leverages top AI models for tasks like document creation, research, image generation, and instant answers. It allows users to command AI with their voice to produce written content, analyze data, and manage documents.

Voice-first AI interactionImage generation from voice commandsInstant, accurate answers via Smart AI Routing
📊 Productivity
(1.7K)
free with in-app purchases
18
Nomi: AI Companion with a Soul
Nomi: AI Companion with a Soul
Nomi: AI Companion with a Soul
Confidant Girlfriend Boyfriend
Free

Engage in dynamic conversations with a highly personalized AI companion that remembers your interactions and evolves with you. Explore imaginative scenarios, create stories, and enjoy real-time voice and photo sharing. This AI offers a judgment-free space for deep discussions or lighthearted banter.

Emotionally intelligent AIShort and long-term memoryAI-generated selfies
🌟 Lifestyle
(2.2K)
free with in-app purchases
19
Jupi - AI Chat & Friend Game
Jupi - AI Chat & Friend Game
Jupi - AI Chat & Friend Game
Create & Chat with AI Chatbots
Free

Create and interact with custom AI characters, from historical figures to fantasy beings. Engage in immersive adventures, ask questions to an AI assistant, and share your creations with others.

Create custom AI charactersChat with 20,000+ AI charactersAI-driven interactive adventures
🎬 Entertainment
(34K)
free with in-app purchases
20
Personal AI
Personal AI
Personal AI
Your Knowledge, Amplified
Free

This platform allows professionals in regulated industries to create a private, secure digital twin of their knowledge. It automates tasks, facilitates collaboration, and offers secure messaging, all while prioritizing data privacy and enterprise-grade security.

Private digital twin of knowledgeSeamless workflow automationPersonalized AI personas
📊 Productivity
(43)
free with in-app purchases

FAQ about Uptodate AI

What are the best uptodate ai apps for iPhone?
UpToDate Expert AI tops our uptodate ai apps ranking as of May 2026, with a 4.8-star average from 544 App Store ratings, and it's free to download.
Yes — 20 of the top uptodate ai apps we rank are free to download, including UpToDate Expert AI and UpToDate.
UpToDate Expert AI has no ads and has no in-app purchases, according to its App Store listing as of May 2026.
We track 235+ uptodate ai apps on the iOS App Store as of May 2026, ranked by rating, recency, and analysis of real user reviews.
UpToDate Expert AI is an AI-powered companion app for the UpToDate clinical decision support platform. It provides medical professionals with fast, evidence-based answers to clinical questions, helping them explore diagnoses and make decisions.
The Expert AI companion app is currently available to select Enterprise Edition accounts. To gain access, you need to contact your Enterprise account lead.